Isle Casino Cape Girardeau at a glance
About Isle Casino Cape Girardeau
Isle Casino Cape Girardeau is a commercial gaming facility in Cape Girardeau, Missouri, operated by Vici Properties. Opened in 2012 as one of Missouri’s newer commercial casinos, the property runs approximately 900 slot machines and 21 table games — including 3 Card Poker, Blackjack, Craps, Flop Poker, Let It Ride Bonus Poker, Mini-Baccarat, Mississippi Stud, and Roulette — on a 24/7 schedule, with a buffet, bar, restaurant, self-parking, and valet on site. The minimum gambling age is 21, regulated by the Missouri Gaming Commission.
Venue photo
Isle Casino
Cape Girardeau, Missouri
Cape Girardeau is the largest city in southeastern Missouri, in Cape Girardeau County on the Mississippi River approximately 100 miles south of St. Louis via I-55. It is home to Southeast Missouri State University and serves as the regional economic center for southeastern Missouri, southern Illinois, and western Kentucky. Isle Casino opened in 2012 as Cape Girardeau’s commercial gaming destination — the only casino within approximately 100 miles of the city.
Games at Isle Casino Cape Girardeau
- caesars rewards
Specific earn rates, tier requirements, and benefits change frequently — confirm with the property's player services desk before your visit.
What the directory data shows
Strengths and gaps inferred from games, features, and directory data.
Strengths
2- 21 tables with Mini-Baccarat, Flop Poker, and Mississippi Stud; buffet and valet; 2012 construction
- Cape Girardeau is southeastern Missouri's largest city — sole casino for 100-mile radius
Watch-outs
1- 900 machines and 21 tables; no hotel on site; Cape Girardeau is approximately 100 miles from St. Louis
Vici Properties' Cape Girardeau casino — 900 slots, 21 tables with Mini-Baccarat and Mississippi Stud, buffet, and 24/7 gaming in southeastern Missouri
Isle Casino Cape Girardeau opened in 2012 as southeastern Missouri's commercial gaming destination — the only casino within approximately 100 miles of Cape Girardeau. The 21-table floor includes Mini-Baccarat, Flop Poker, and Mississippi Stud alongside standard Blackjack and Craps. Caesars Rewards earns across the Caesars national portfolio. Confirm current promotions with the property directly.
Licensing & Rules
- Regulator
- Missouri Gaming Commission
- Age Requirement
- 21+
- Sportsbook
- Legal (retail only)





